Do not ever administer a dogs product to your cat or a cats product to your dog. Why Shouldnt You Use Advantage Multi for Dogs on Cats? Though Advantage Multi for dogs and advantage multi for cats prevent the same parasites (fleas, heartworms, hookworms, whipworms and roundworms) in both the pets, they have a different effect on their systems. The proportion of Imidacloprid and moxidectin in the two products vary.