How many rounds of parvo shots do puppies need? Asked By: Betsy Hane. Date created: Sat, Feb 13, 2021 9:01 AM. Best answers. Canine Distemper, Adenovirus (Hepatitis), Parvovirus, and Parainfluenza are usually taken care of via a single shot known as a 5-Way Combination Vaccine or a 5 in 1 Vaccine, while rabies is always handled separately. Answered By: Kian King. Date created: Sun, Feb 14, 2021 11:04 AM. FAQ. =I At what age do puppies get parvo shots? These will include the core ...