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Most puppy mouthing is normal behavior. However, some puppies bite out of fear or frustration, and this type of biting can signal problems with future aggression. Puppies sometimes have temper tantrums. Usually tantrums happen when you're making a puppy do something he doesn't like.
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Dealing with Normal Puppy Behavior: Nipping and Rough Play.

When puppies play with each other, they use their mouths.

Therefore, puppies usually want to bite or "mouth" hands during play or when being petted.

With puppies, this is rarely aggressive behavior in which the intent is to do harm.

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