Lupo I or Lupus I of Aquitaine, Duke of Gascony and part of Aquitaine in the 670s. Lupo II of Gascony (died 778), Duke of Gascony. Lupo III Centule of Gascony, Duke of Gascony from 818 to 819. Lupo (surname), persons having the surname Lupo. Lupo, the Italian nickname of Bulgaria-born volleyball player Lyubomir Ganev.