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Briefly:



  1. Cells are exposed to parvovirus and take it up.

  2. Some trigger causes parvovirus to release its genetic
    material.

  3. Host cells begin to replicate the parvovirus; parvovirus is
    100% dependent on its host for replication machinery.

  4. Viral particles are released.
    Specifically:
    Canine parvovirus is a small non-encapsulated single-stranded
    DNA virus related to feline panleukopenia virus. It binds to the
    canine (and in some cases feline) transferrin receptor. It is
    probably taken up through clathrin-mediated endocytosis according
    to Parrish et al in J Virol 2004 Jul;78(13):6709-14. An as-yet
    unknown trigger causes the release of its ssDNA. The DNA then uses
    host ribosomes to synthesize its VP1 and VP2 (capsid) proteins as
    well as its NS1 and NS

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