Lupo may refer to: . People. Lupo I or Lupus I of Aquitaine, Duke of Gascony and part of Aquitaine in the 670s; Lupo II of Gascony (died 778), Duke of Gascony; Lupo III Centule of Gascony, Duke of Gascony from 818 to 819; Lupo (surname), persons having the surname Lupo Lupo, the Italian nickname of Bulgaria-born volleyball player Lyubomir Ganev