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The standard dosage for oral Benadryl is 1 mg per pound of body weight, given 2-3 times a day.

Most drug store diphenhydramine tablets are 25 mg, which is the size used for a 25 pound dog.

Always double check the dosage before giving an over the counter medication.

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The most common antihistamine for dogs is diphenhydramine, brand name Benadryl. Also found in ProSense Dog Itch & Allergy Solutions Tablets, diphenhydramine is safe in most dogs if given in the recommended dosage of 1 mg of diphenhydramine per pound of body weight given by mouth.

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