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Abnormalities in the CNS can cause increased appetite, as can several other factors such as stress, an underlying disease, or a tumor.

Because appetite changes are so common in many illnesses and situations, diagnosing the reason for it can be a complex process.

Polyphagia can indicate serious disease.

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The most common causes of polyphagia in the dog are hyperadrenocorticism (cushings), diabetes mellitus, parasitism, and pancreatic insufficiency. The most common causes of polyphagia in the cat include hyperthyroidism and diabetes mellitus.

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