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  1. Puppy's first shots. Puppies need their first vaccinations at six to eight weeks old.
  2. When to vaccinate? Vaccines are only effective once a puppy has been weaned.
  3. Must-have shots. All puppies should be immunized against parvovirus, distemper, rabies and hepatitis.
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When To Start Puppy Vaccinations

In general, a puppy should start vaccines as soon as you get the puppy (this is usually between 6 and 8 weeks) and then every three weeks until approximately four months of age when it will receive the final round.

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